Ortho's CDG EstroDim is one of the only formulas available that combines
three important ingredients--DIM + I3C + Calcium D-Glucarate--in an easy
compliance dose.
Why These Natural Ingredients?
Women's Health:
Calcium D-Glucorate
In the detoxification process some metabolites may become more harmful
prior to their final elimination from the body. Glucuronic acid is often
attached to these metabolites prior to their elimination. Certain gut bacteria
are capable of releasing these metabolites via the activity of the glucuronidase
enzyme and allowing them to recirculate with potentially harmful consequences.
The glucarate delivered by calcium D-glucorate is capable of inhibiting this
glucuronidase and reducing the harmful burden on the body.
Indole-3-Carbinol
Human clinical trials show an improvement in 2/16 hydroxy-estrone
ratios in women taking I3C, demonstrating its value in helping lower risk
in these women.
Folic Acid
The proper processing of estrogen metabolites requires folic acid. Folic
acid deficiency, especially alcohol-related, increases risk for estrogen-related
breast conditions.
Men’s Health:
Calcium D-Glucorate
Just as in women, men also can have hormonerelated conditions, most
common of which are issues with the prostate. The body’s natural detoxification
process can unearth negative consequences where some metabolites may become
more harmful prior to their final elimination from the body. Glucuronic acid
is often attached to these metabolites prior to their elimination. Certain
gut bacteria are capable of releasing these metabolites via the activity
of the glucuronidase enzyme and allowing them to recirculate with potentially
harmful consequences. The glucarate delivered by calcium D-glucorate is capable
of inhibiting this glucuronidase and reducing the harmful burden on the body.
Indole-3-Carbinol
I3C is considered one of the main active ingredients accounting
for the health benefits found in cruciferous vegetables. I3C, and many of
its metabolites including DIM, have been investigated with in vitro and animal
studies using susceptible cell and animal lines.
Folic Acid
The proper processing of estrogen metabolites requires folic acid.
Folic acid deficiency, especially alcohol-related, increases risk for conditions
relating to the prostate.
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