The use of Indole-3-carbinol and its metabolite Diindolylmethane has
come into use due to the historical aspects of diets high in cruciferous
Why These Natural Ingredients?
Human clinical trials show an improvement in 2/16 hydroxy-estrone ratios
in women taking I3C, demonstrating its value in helping lower risk
in these women.
I3C is considered one of the main active ingredients accounting for the
health benefits found in cruciferous vegetables. I3C, and many of its
metabolites including DIM, have been investigated with in vitro, animal
and human studies.